Cats Claw Herb Mao Zhua Cao: The TCM Herb for Reducing Swelling and Detoxification
- Hongji Medical
- Jun 11
- 4 min read
Mao Zhua Cao, also known as Cat’s Claw Herb or Ranunculus ternatus, is the dried tuberous root of a plant in the buttercup family, named for its roots’ resemblance to tiny cat claws. This herb is valued in Traditional Chinese Medicine (TCM) for its ability to reduce swelling, disperse nodules, and clear toxins. In recent years, it has gained attention for its potential in treating various conditions, including tumors and infections.

While Cats Claw Herb Mao Zhua Cao is not explicitly mentioned in ancient classics like the Shennong Bencao Jing or Compendium of Materia Medica, its use is well-documented in regional and modern herbal texts, such as Zhejiang Folk Herbal Medicine and Anhui Chinese Herbal Medicine. These sources describe its role in treating swollen lymph nodes, sores, and snakebites. Folk traditions have long relied on Mao Zhua Cao for managing lumps and inflammation, and modern research is expanding its applications within TCM.

Properties of Cats Claw Herb Mao Zhua Cao
Nature and Channels
Taste: Pungent
Nature: Warm
Channels: Liver, Lung
Main Benefits
Disperses nodules and reduces swelling
Clears heat and detoxifies
Supports anti-tumor effects
Dosage
Internal use: 15–30 grams, boiled in decoctions.
External use: Applied as a poultice, as needed.
Growing Regions
Found in the Yangtze River basin and southern China, including Jiangsu, Zhejiang, Anhui, Jiangxi, Hunan, and Hubei.
Identification
Shape: Clusters of spindle-shaped tuberous roots, resembling cat claws, 0.5–1.5 cm long, 0.3–0.5 cm in diameter.
Color: Brownish or grayish-brown with irregular longitudinal wrinkles.
Texture: Brittle, easily broken, with a white or grayish-white, powdery cross-section.
Scent and Taste: Mild scent, pungent, slightly bitter taste.
Preparation
Used raw or vinegar-fried. Vinegar-frying enhances its ability to disperse nodules and relieve pain.
Clinical Uses of Cats Claw Herb Mao Zhua Cao
Mao Zhua Cao is used in TCM to treat various conditions:
Scrofula (Lymph Node Tuberculosis): Relieves swollen, hard, and painful lymph nodes in the neck, often with low-grade fever or fatigue.
Goiter (Thyroid Enlargement): Helps reduce simple thyroid swelling.
Toxic Sores: Treats red, painful, and pus-filled skin conditions like boils or abscesses.
Snakebites: Eases swelling and pain from venomous bites.
Lung Cancer: Used as an adjunct therapy to inhibit tumor growth.
Specific Benefits
Dispersing Nodules and Reducing Swelling: Contains alkaloids and flavonoids that reduce inflammation and swelling.
Clearing Heat and Detoxifying: Neutralizes toxins, promoting healing of sores and infections.
Anti-Tumor Support: May inhibit tumor cell growth, aiding cancer treatment.

Mao Zhua Cao in TCM Formulas
Mao Zhua Cao is often combined with other herbs in TCM formulas to enhance its effects. Here are some examples:
Mao Zhua Cao San Jie Tang (Cat’s Claw Nodule-Dispersing Decoction): Combines Mao Zhua Cao with Prunella, Oyster Shell, Fritillaria, Scrophularia, and Licorice to disperse nodules, used for scrofula and goiter.
Mao Zhua Cao Jie Du Tang (Cat’s Claw Detoxification Decoction): Includes Mao Zhua Cao with Honeysuckle, Forsythia, Dandelion, Viola, and Licorice to clear toxins, treating sores and snakebites.
Hua Tan San Jie Fang (Phlegm-Dissolving and Nodule-Dispersing Formula): Pairs Mao Zhua Cao with Pinellia, Tangerine Peel, Fritillaria, Oyster Shell, Seaweed, Kelp, Cremastra, and Silkworm to dissolve phlegm and nodules, used for thyroid nodules.
Comparison with Similar Herbs
Mao Zhua Cao shares properties with other TCM herbs but has unique strengths:
Prunella (Xia Ku Cao): Clears liver heat and disperses nodules but excels in treating eye pain and headaches from liver fire.
Forsythia (Lian Qiao): Clears heat and detoxifies but is better for wind-heat colds and sore throats.
Dandelion (Pu Gong Ying): Clears heat, detoxifies, and reduces swelling but also promotes urination, ideal for infections.
Mao Zhua Cao is particularly effective for dispersing hard nodules and treating scrofula, while others focus on different heat-related conditions.
Modern Applications and Research
Modern research highlights Mao Zhua Cao’s benefits:
Anti-Tumor Effects: Its extracts inhibit lung, liver, and leukemia cancer cells, potentially by inducing cell death and blocking blood vessel growth.
Anti-Inflammatory: Reduces inflammation by suppressing mediators.
Immune Support: Enhances immune function, boosting resistance.
Antibacterial: Inhibits certain bacteria and fungi.
Clinically, Mao Zhua Cao is used as an adjunct for lung cancer, liver cancer, and leukemia, improving outcomes and reducing side effects. It also shows promise for autoimmune conditions like rheumatoid arthritis and lupus.
Research Directions
Active Compounds: Identifying key components and their mechanisms for new drug development.
Formulations: Creating convenient forms like injections, syrups, or capsules.
Clinical Trials: Conducting large-scale studies to confirm efficacy and safety.
How to Use Mao Zhua Cao Safely
Precautions
Yin Deficiency with Heat: Use cautiously, as its warm nature may worsen heat symptoms.
Long-Term Use: Avoid prolonged high doses to prevent side effects.
Pregnant Women: Consult a practitioner, as safety data is limited.
Usage Tips
Vinegar-fried Mao Zhua Cao is preferred for nodule-dispersing effects. Consult a TCM practitioner for proper dosage and suitability.
Conclusion
Mao Zhua Cao is a valuable TCM herb known for dispersing nodules, reducing swelling, and detoxifying. It effectively treats scrofula, goiter, sores, and snakebites, with modern research supporting its anti-tumor and immune-boosting properties. As studies continue, Mao Zhua Cao’s role in healthcare may grow, offering new possibilities for treatment. To ensure safe and effective use, consult a TCM practitioner for guidance on dosage and preparation.